Evaluation of GenoFlow DR-MTB array test for detection of rifampin and isoniazid resistance in mycobacterium tuberculosis

Molina-Moya, B. ; Kazdaglis, G. ; Lacoma, A. ; Prat, C. ; Gómez, A. ; Villar-Hernández, R. ; García-García, E. ; Haba, L. ; Maldonado, J. ; Samper, S. ; Ruiz-Manzano, J. ; Ausina, V. ; Domínguez, J.

Resumen: The aim of this study was to evaluate the GenoFlow DR-MTB array test (DiagCor Bioscience, Hong Kong) on 70 cultured isolates and 50 sputum specimens. The GenoFlow array test showed good sensitivity and specificity compared to the phenotypic Bactec 460TB. This array accurately detected mutations in rpoB, katG, and inhA associated with resistance to rifampin and isoniazid.

Idioma: Inglés

DOI: 10.1128/JCM.03341-15

Año: 2016

Publicado en: JOURNAL OF CLINICAL MICROBIOLOGY 54, 4 (2016), 1160-1163
ISSN: 0095-1137

Factor impacto JCR: 3.712 (2016)

Categ. JCR: MICROBIOLOGY rank: 33 / 124 = 0.266 (2016) - Q2 - T1

Factor impacto SCIMAGO: 2.196 - Microbiology (medical) (Q1)

Financiación: info:eu-repo/grantAgreement/ES/FIS/PI13-05146

Tipo y forma: Article (Published version)