Covalent immobilisation of magnetic nanoparticles on surfaces via strain-promoted azide-alkyne click chemistry
Fratila, Raluca M. ; Navascuez, Marcos ; Idiago-López, Javier ; Ezeiza, Maite ; Miranda, José I. ; Aizpurua, Jesús M. ; Martínez de la Fuente, Jesús (Universidad de Zaragoza)
Resumen: Herein we report the synthesis of “clickable” magnetic nanoparticles (MNPs) stable in suspension in physiological media for bioorthogonal click chemistry applications. These MNPs incorporate into their coating a cyclooctynyl derivative for strain-promoted azide–alkyne (SPAAC) cycloaddition and either a polyethylene glycol or a glucose moiety to ensure MNP stability in physiological media. Their reactivity towards azide-functionalised Si surfaces was investigated, demonstrating their potential as bioorthogonal probes.
Idioma: Inglés
DOI: 10.1039/c7nj01822c
Año: 2017
Publicado en: NEW JOURNAL OF CHEMISTRY 19 (2017), [6 pp.]
ISSN: 1144-0546
Factor impacto JCR: 3.201 (2017)
Categ. JCR: CHEMISTRY, MULTIDISCIPLINARY rank: 65 / 171 = 0.38 (2017) - Q2 - T2
Factor impacto SCIMAGO: 0.864 - Chemistry (miscellaneous) (Q1) - Materials Chemistry (Q1) - Catalysis (Q2)
Financiación: info:eu-repo/grantAgreement/EC/H2020/657215/EU/Cell-surface immobilized vs. internalized magnetic nanoparticles for magnetic hyperthermia studies/OUTstandINg
Financiación: info:eu-repo/grantAgreement/ES/MINECO/SAF2014-54763-C2-2-R
Financiación: info:eu-repo/grantAgreement/ES/UZ/JIUZ-2015-CIE-03
Tipo y forma: Article (PrePrint)
Área (Departamento): Área Química Orgánica (Dpto. Química Orgánica)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material.
Exportado de SIDERAL (2019-07-09-11:31:51)
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Idioma: Inglés
DOI: 10.1039/c7nj01822c
Año: 2017
Publicado en: NEW JOURNAL OF CHEMISTRY 19 (2017), [6 pp.]
ISSN: 1144-0546
Factor impacto JCR: 3.201 (2017)
Categ. JCR: CHEMISTRY, MULTIDISCIPLINARY rank: 65 / 171 = 0.38 (2017) - Q2 - T2
Factor impacto SCIMAGO: 0.864 - Chemistry (miscellaneous) (Q1) - Materials Chemistry (Q1) - Catalysis (Q2)
Financiación: info:eu-repo/grantAgreement/EC/H2020/657215/EU/Cell-surface immobilized vs. internalized magnetic nanoparticles for magnetic hyperthermia studies/OUTstandINg
Financiación: info:eu-repo/grantAgreement/ES/MINECO/SAF2014-54763-C2-2-R
Financiación: info:eu-repo/grantAgreement/ES/UZ/JIUZ-2015-CIE-03
Tipo y forma: Article (PrePrint)
Área (Departamento): Área Química Orgánica (Dpto. Química Orgánica)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material. Exportado de SIDERAL (2019-07-09-11:31:51)
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Record created 2017-10-09, last modified 2019-07-09