Síndrome de Austrian: Una rara manifestación de la enfermedad neumocócica invasiva. Presentación de un caso y revisión bibliográfica
Rodríguez Nogué, M. ; Gómez Arraiz, I. ; Ara Martín, G. ; Fraj Valle, M.M. ; Gómez Peligros, A. (Universidad de Zaragoza)
Resumen: El síndrome de Austrian es una patología producida por la infección diseminada de Streptococcus pneumoniae y caracterizada por la tríada de neumonía, endocarditis y meningitis Tiene una incidencia estimada de 0,9-7,8 casos por diez millones de habitantes y año y una mortalidad del 32%. El consumo de alcohol, como principal factor de riesgo, aparece solamente en cuatro de cada diez pacientes. Un 14% no presentan factores de riesgo. Dos de cada tres enfermos son varones y ocurre en la época media de la vida. Asienta sobre válvula nativa, lesionándose la aorta en la mitad de los afectados. Presentan regurgitación severa dos de cada tres pacientes. El tratamiento antimicrobiano apropiado y la cirugía temprana de la endocarditis disminuyen la mortalidad. Es posible que la epidemiología del síndrome de Austrian esté cambiando por la introducción de la vacuna antineumocócica conjugada 13-valente en el calendario infantil.
The Austrian syndrome is a pathology caused by disseminated Streptococcus pneumoniae infection and characterized for the triad of pneumonia, endocarditis and meningitis. It has an estimated incidence of 0.9-7.8 cases per ten millions people each year, and a mortality of 32%. Alcohol abuse, as the main risk factor, appears only in four out of ten patients. Moreover, 14% of patientes do not have any risk factor. Two out of three patients are males and it occurs in the middle aged of life. It is more frequently on native valve, aortic valve is injured in the half of the cases. Severe regurgitation occurs in two per three patients. Appropriate antimicrobial treatment and early endocarditis surgery decrease mortality. It is possible that Austrian syndrome epidemiology is changing by the introduction of 13-valent pneumococcal conjugated vaccine in the children´s calendar.
Idioma: Español
Año: 2019
Publicado en: Revista española de quimioterapia 32, 2 (2019), 98-113
ISSN: 1988-9518
Originalmente disponible en: Texto completo de la revista
Factor impacto JCR: 1.132 (2019)
Categ. JCR: PHARMACOLOGY & PHARMACY rank: 246 / 270 = 0.911 (2019) - Q4 - T3
Categ. JCR: MICROBIOLOGY rank: 121 / 134 = 0.903 (2019) - Q4 - T3
Factor impacto SCIMAGO: 0.287 - Medicine (miscellaneous) (Q3) - Pharmacology (Q3) - Microbiology (medical) (Q3)
Tipo y forma: Review (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes.
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The Austrian syndrome is a pathology caused by disseminated Streptococcus pneumoniae infection and characterized for the triad of pneumonia, endocarditis and meningitis. It has an estimated incidence of 0.9-7.8 cases per ten millions people each year, and a mortality of 32%. Alcohol abuse, as the main risk factor, appears only in four out of ten patients. Moreover, 14% of patientes do not have any risk factor. Two out of three patients are males and it occurs in the middle aged of life. It is more frequently on native valve, aortic valve is injured in the half of the cases. Severe regurgitation occurs in two per three patients. Appropriate antimicrobial treatment and early endocarditis surgery decrease mortality. It is possible that Austrian syndrome epidemiology is changing by the introduction of 13-valent pneumococcal conjugated vaccine in the children´s calendar.
Idioma: Español
Año: 2019
Publicado en: Revista española de quimioterapia 32, 2 (2019), 98-113
ISSN: 1988-9518
Originalmente disponible en: Texto completo de la revista
Factor impacto JCR: 1.132 (2019)
Categ. JCR: PHARMACOLOGY & PHARMACY rank: 246 / 270 = 0.911 (2019) - Q4 - T3
Categ. JCR: MICROBIOLOGY rank: 121 / 134 = 0.903 (2019) - Q4 - T3
Factor impacto SCIMAGO: 0.287 - Medicine (miscellaneous) (Q3) - Pharmacology (Q3) - Microbiology (medical) (Q3)
Tipo y forma: Review (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. Exportado de SIDERAL (2020-10-29-14:05:45)
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Record created 2019-05-09, last modified 2020-10-29