Update on the Immune Mechanisms Against Respiratory Pathogens

Garmendia, Junkal ; Gonzalo-Asensio, Jesús (Universidad de Zaragoza)

Resumen: Respiratory infections pose a continuous threat to humans due to their easy dissemination via aerial transmission. As a consequence, they are leading causes of mortality and morbidity worldwide. Lower respiratory tract infections (LRTI) remained the deadliest communicable diseases causing 3 million deaths worldwide in 2016 (1). Similarly, although the number of tuberculosis (TB) deaths tends to decrease, it is still among the top 10 causes of global mortality with a yearly death burden of about 1.6 million (2). The growing emergence of bacterial antibiotic resistance is a major global challenge for the coming years, and several major respiratory pathogens are included in the WHO priority list of bacteria for which new antibiotics are urgently needed (3). In terms of target population, children under the age of five are the most susceptible hosts to a plethora of respiratory pathogens.

Idioma: Inglés

DOI: 10.3389/fimmu.2019.01730

Año: 2019

Publicado en: FRONTIERS IN IMMUNOLOGY 10 (2019), 1730 [4 pp.]
ISSN: 1664-3224

Factor impacto JCR: 5.085 (2019)

Categ. JCR: IMMUNOLOGY rank: 38 / 158 = 0.241 (2019) - Q1 - T1

Factor impacto SCIMAGO: 2.116 - Immunology and Allergy (Q1) - Immunology (Q1)

Financiación: info:eu-repo/grantAgreement/ES/MINECO/BFU2015-72190-EXP
Financiación: info:eu-repo/grantAgreement/ES/MINECO/RTI2018-096369-B-I00
Financiación: info:eu-repo/grantAgreement/ES/MINECO/SAF2015-66520-R

Tipo y forma: (Published version)

Área (Departamento): Área Microbiología (Dpto. Microb.Med.Pr.,Sal.Públ.)