Stronger induction of trained immunity by mucosal BCG or MTBVAC vaccination compared to standard intradermal vaccination
Vierboom, M.P.M. ; Dijkman, K. ; Sombroek, C.C. ; Hofman, S.O. ; Boot, C. ; Vervenne, R.A.W. ; Haanstra, K.G. ; van der Sande, M. ; van Emst, L. ; Domínguez-Andrés, J. ; Moorlag, S.J.C.F.M. ; Kocken, C.H.M. ; Thole, J. ; Rodríguez, E. ; Puentes, E. ; Martens, J.H.A. ; van Crevel, R. ; Netea, M.G. ; Aguilo, N. (Universidad de Zaragoza) ; Martin, C. (Universidad de Zaragoza) ; Verreck, F.A.W.
Resumen: Vierboom et al. demonstrate the induction of trained immunity in blood and bone marrow monocytes after vaccination with live attenuated TB vaccines in nonhuman primates. Mucosal respiratory delivery of BCG or MTBVAC induces trained immunity more efficiently compared to standard intradermal vaccination.
Idioma: Inglés
DOI: 10.1016/j.xcrm.2020.100185
Año: 2021
Publicado en: Cell reports medicine 2, 1 (2021), 100185 [20 pp]
ISSN: 2666-3791
Factor impacto JCR: 16.988 (2021)
Categ. JCR: MEDICINE, RESEARCH & EXPERIMENTAL rank: 5 / 140 = 0.036 (2021) - Q1 - T1
Categ. JCR: CELL BIOLOGY rank: 17 / 195 = 0.087 (2021) - Q1 - T1
Factor impacto CITESCORE: 7.1 - Biochemistry, Genetics and Molecular Biology (Q2)
Factor impacto SCIMAGO: 5.956 - Biochemistry, Genetics and Molecular Biology (miscellaneous) (Q1)
Financiación: info:eu-repo/grantAgreement/EC/H2020/643381/EU/TBVAC2020; Advancing novel and promising TB vaccine candidates from discovery to preclinical and early clinical development/TBVAC2020
Financiación: info:eu-repo/grantAgreement/EC/H2020/730964/EU/European Vaccine Research and Development Infrastructure/TRANSVAC2
Tipo y forma: Article (Published version)
Área (Departamento): Área Microbiología (Dpto. Microb.Ped.Radio.Sal.Pú.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material.
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Idioma: Inglés
DOI: 10.1016/j.xcrm.2020.100185
Año: 2021
Publicado en: Cell reports medicine 2, 1 (2021), 100185 [20 pp]
ISSN: 2666-3791
Factor impacto JCR: 16.988 (2021)
Categ. JCR: MEDICINE, RESEARCH & EXPERIMENTAL rank: 5 / 140 = 0.036 (2021) - Q1 - T1
Categ. JCR: CELL BIOLOGY rank: 17 / 195 = 0.087 (2021) - Q1 - T1
Factor impacto CITESCORE: 7.1 - Biochemistry, Genetics and Molecular Biology (Q2)
Factor impacto SCIMAGO: 5.956 - Biochemistry, Genetics and Molecular Biology (miscellaneous) (Q1)
Financiación: info:eu-repo/grantAgreement/EC/H2020/643381/EU/TBVAC2020; Advancing novel and promising TB vaccine candidates from discovery to preclinical and early clinical development/TBVAC2020
Financiación: info:eu-repo/grantAgreement/EC/H2020/730964/EU/European Vaccine Research and Development Infrastructure/TRANSVAC2
Tipo y forma: Article (Published version)
Área (Departamento): Área Microbiología (Dpto. Microb.Ped.Radio.Sal.Pú.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material. Exportado de SIDERAL (2023-05-18-13:36:49)
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Record created 2021-03-09, last modified 2023-05-19