Burden of bacterial antimicrobial resistance among hospitalised patients in Spain: findings from three nationwide prospective studies
Peñalva, Germán ; Cantón, Rafael ; Pérez-Rodríguez, María Teresa ; González-López, Juan José ; Rodríguez-Baño, Jesús ; Barrio-Tofiño, Ester del ; Kirkegaard-Biosca, Cristina ; Sánchez-Romero, Isabel ; Gutiérrez-Villanueva, Andrea ; Marrodán-Ciordia, Teresa ; Guerra-Laso, José Manuel ; Rosario-Quintana, Cristóbal del ; Suárez-Hormiga, Laura ; Cámara, Jordi ; Puig-Asensio, Mireia ; Heredero, Eva ; Sepúlveda, María Antonia ; Rodríguez-Díaz, Juan Carlos ; Merino, Esperanza ; Cercenado, Emilia ; Villa, Sofia de la ; Siller, María ; Arnaiz, Francisco ; Seral, Cristina (Universidad de Zaragoza) ; Lepe, José Antonio ; Cisneros, José Miguel ; Paño-Pardo, José Ramón (Universidad de Zaragoza) ; Castiillo García, Francisco (Universidad de Zaragoza)
Resumen: Background: Assessing the burden of antimicrobial resistance is essential to determine the magnitude of this problem and to set its priority. We aimed to estimate the burden of disease caused by multidrug-resistant microorganisms (MDRO) in hospitalised patients in Spain.
Methods: Three prospective nationwide studies were conducted in 2018, 2019 and 2023. All patients with a new diagnosis of infection with any of 10 selected MDROs plus Clostridioides difficile during the study period (one week in 2018 and 2019 and two weeks in 2023) were included. Patient demographic, and clinical outcomes were analysed, including incidence, crude all-cause 30-day mortality and years of life lost (YLL). These results were used to calculate weighted and seasonally adjusted annual estimates for the whole country.
Idioma: Inglés
DOI: 10.1016/j.lanepe.2025.101220
Año: 2025
Publicado en: The Lancet Regional Health - Europe 51 (2025), 101220 [13 pp.]
ISSN: 2666-7762
Tipo y forma: Article (Published version)
Área (Departamento): Área Microbiología (Dpto. Microb.Ped.Radio.Sal.Pú.)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material.
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Methods: Three prospective nationwide studies were conducted in 2018, 2019 and 2023. All patients with a new diagnosis of infection with any of 10 selected MDROs plus Clostridioides difficile during the study period (one week in 2018 and 2019 and two weeks in 2023) were included. Patient demographic, and clinical outcomes were analysed, including incidence, crude all-cause 30-day mortality and years of life lost (YLL). These results were used to calculate weighted and seasonally adjusted annual estimates for the whole country.
Idioma: Inglés
DOI: 10.1016/j.lanepe.2025.101220
Año: 2025
Publicado en: The Lancet Regional Health - Europe 51 (2025), 101220 [13 pp.]
ISSN: 2666-7762
Tipo y forma: Article (Published version)
Área (Departamento): Área Microbiología (Dpto. Microb.Ped.Radio.Sal.Pú.)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material. Exportado de SIDERAL (2025-10-17-14:31:51)
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Articles > Artículos por área > Microbiología
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Record created 2025-02-14, last modified 2025-10-17