Effects of exercise on the cognition of older women treated with lovastatin
Molina-Sotomayor, E. ; Arreguin-Moreno, R. ; Rodriguez, F. ; Pradas, F. (Universidad de Zaragoza) ; Leon, J.A. ; Gonzalez-Jurado, J.A.
Resumen: Introduction: The deterioration of cognition is highly predominant in older adults. Objective: The aim of this study was to analyse the effects of a walk program on the cognition and blood concentration of lipids in women over 60 years of age who were being treated with Lovastatin.
Materials and methods: Participants were distributed in two groups: an exercise group (EG, n=45) with aerobic training and an inactive sedentary group (SG, n=22). The cognitive state of the subjects was assessed through the Spanish Mini-Cog Test version of the MMSE; lipoproteins were quantified using a lipid profile test and the cardiorespiratory fitness was measured using the 6 min Walk Test (6MWT).
Results: EG showed a significant increase (p<0.05) in cardiorespiratory fitness and in HDL-C concentrations. Furthermore, the results from the cognition tests showed a large effect size in spatial orientation and attention and calculation. The decrease in LDL-C was not significant (p>0.05).
Conclusion: A controlled and progressive walk program for older women treated with Lovastatin may induce a boost of brain activity linked to HDL-C, which could delay cognitive impairment.
Idioma: Inglés
DOI: 10.3233/JAD-170014
Año: 2018
Publicado en: Biomedica 38, 4 (2018), [33 pp]
ISSN: 0120-4157
Factor impacto JCR: 0.733 (2018)
Categ. JCR: TROPICAL MEDICINE rank: 17 / 21 = 0.81 (2018) - Q4 - T3
Factor impacto SCIMAGO: 0.276 - Medicine (miscellaneous) (Q3) - Biochemistry, Genetics and Molecular Biology (miscellaneous) (Q3)
Tipo y forma: Article (Published version)
Área (Departamento): Área Didáctica Expres.Corporal (Dpto. Expres.Music.Plást.Corp.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes.
Exportado de SIDERAL (2024-01-04-11:02:31)
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Materials and methods: Participants were distributed in two groups: an exercise group (EG, n=45) with aerobic training and an inactive sedentary group (SG, n=22). The cognitive state of the subjects was assessed through the Spanish Mini-Cog Test version of the MMSE; lipoproteins were quantified using a lipid profile test and the cardiorespiratory fitness was measured using the 6 min Walk Test (6MWT).
Results: EG showed a significant increase (p<0.05) in cardiorespiratory fitness and in HDL-C concentrations. Furthermore, the results from the cognition tests showed a large effect size in spatial orientation and attention and calculation. The decrease in LDL-C was not significant (p>0.05).
Conclusion: A controlled and progressive walk program for older women treated with Lovastatin may induce a boost of brain activity linked to HDL-C, which could delay cognitive impairment.
Idioma: Inglés
DOI: 10.3233/JAD-170014
Año: 2018
Publicado en: Biomedica 38, 4 (2018), [33 pp]
ISSN: 0120-4157
Factor impacto JCR: 0.733 (2018)
Categ. JCR: TROPICAL MEDICINE rank: 17 / 21 = 0.81 (2018) - Q4 - T3
Factor impacto SCIMAGO: 0.276 - Medicine (miscellaneous) (Q3) - Biochemistry, Genetics and Molecular Biology (miscellaneous) (Q3)
Tipo y forma: Article (Published version)
Área (Departamento): Área Didáctica Expres.Corporal (Dpto. Expres.Music.Plást.Corp.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. Exportado de SIDERAL (2024-01-04-11:02:31)
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Record created 2018-12-19, last modified 2024-01-04