Development and validation of a method for the analysis of halophenols and haloanisoles in cork bark macerates by stir bar sorptive extraction heart-cutting two-dimensional gas chromatography negative chemical ionization mass spectrometry

Marsol-Vall, A. (Universidad de Zaragoza) ; Ainsa, S. (Universidad de Zaragoza) ; López, R. (Universidad de Zaragoza) ; Ferreira, V. (Universidad de Zaragoza)

Resumen: A method has been developed for the quantitative determination in cork bark macerates of 7halophenols and 5haloanisoles with demonstrated or suspected contribution to the cork taint off-flavour. Macerates were extracted with stirbar (20 mm polydimethylsiloxane-coated) sorptive extraction under optimized conditions (pH 3.5, 20% NaCl and 60 min). The bars were analysed byautomated thermal desorption, heart-cutting two-dimensional gas chromatography and negative chemical ionization-mass spectrometry. Matrix effects were compensated for by a “matrix matched” calibration curve. Limits of detection were in the range 0.03-0.24 ng L-1, below the corresponding odor thresholds. Linearity (0.983 = R2 = 0.998), intra- and inter-day precision (5.4-14.3%) and accuracy (89–126%) were satisfactory. The analysis of 48 natural cork bark samples affected/not-affected bya cryptogamic disease (yellow spot) revealed compositional differences in 2, 4, 6-trichloroanisole (2, 4, 6-TCA), 2, 4, 6-trichlorophenol (2, 4, 6-TCP) and also in 2, 6-dibromophenol, 2, 3, 4- and 2, 4, 5-TCP, 2, 3, 4-TCA and 2, 3, 4, 6-tetrachlorophenol (2, 3, 4, 6-TeCP). In addition, the contents of 2, 4, 6-TCP and 2, 4, 6-TCA, and 2, 3, 4, 6-TeCP and some TCPs presented strong linear correlations.

Idioma: Inglés

DOI: 10.1016/j.chroma.2022.463186

Año: 2022

Publicado en: Journal of Chromatography A 1673 (2022), 463186 [8 pp.]
ISSN: 0021-9673

Factor impacto JCR: 4.1 (2022)

Categ. JCR: CHEMISTRY, ANALYTICAL rank: 25 / 86 = 0.291 (2022) - Q2 - T1
Categ. JCR: BIOCHEMICAL RESEARCH METHODS rank: 21 / 77 = 0.273 (2022) - Q2 - T1

Factor impacto CITESCORE: 7.4 - Biochemistry, Genetics and Molecular Biology (Q2) - Chemistry (Q1) - Medicine (Q1)

Factor impacto SCIMAGO: 0.766 - Analytical Chemistry (Q1) - Organic Chemistry (Q1) - Medicine (miscellaneous) (Q2) - Biochemistry (Q2)

Financiación: info:eu-repo/grantAgreement/ES/MICIU/FJCI-2018-035486-I

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Química Analítica (Dpto. Química Analítica)